Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6573170 | 0.79 | NPC1 (0.57) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL29363181 | 0.77 | RAB9A (0.61) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL59309 | 0.77 | RAB9A (0.61) | NPC1RAB9ALMNAALDH1A1POLB | |
| Methane SCHEMBL10729260 | 0.75 | RAB9A (0.59) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL5666375 | 0.75 | NPC1 (0.43) | NPC1RAB9ALMNAALDH1A1POLB | |
| Acetic Acid SCHEMBL2228922 | 0.75 | NPC1 (0.56) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL3120817 | 0.74 | LMNA (0.41) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL16327310 | 0.74 | KDM4E (0.42) | KDM4EHPGD | |
| SCHEMBL295413 | 0.72 | LMNA (0.40) | NPC1RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL30573273 | 0.71 | LMNA (0.56) | NPC1RAB9ALMNAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144391-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000043376-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-27 | — | — | WO | disclosed |
| US-6040455-A | REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |