Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.72 |
| ▸ | GABRA1 | P14867 | 11/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 11/20 | 0.71 |
| ▸ | CNR2 | P34972 | 4/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.69 |
| ▸ | CNR1 | P21554 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.69 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.69 |
| ▸ | RXRA | P19793 | 1/20 | 0.69 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.69 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.69 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.69 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183124 | 0.86 | AKR1B1 (0.67) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL9197925 | 0.86 | AKR1B1 (0.71) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL4907630 | 0.84 | AKR1B1 (1.00) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL29892631 | 0.84 | GABRA1 (1.00) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL252293 | 0.84 | GABRA1 (1.00) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| Magnatriol B SCHEMBL30058935 | 0.83 | GABRA1 (0.74) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL18306487 | 0.83 | AKR1B1 (0.63) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL2185735 | 0.83 | GABRA1 (0.82) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| SCHEMBL28617501 | 0.82 | AKR1B1 (0.55) | AKR1B1GABRA1GABRB2CNR2ALOX5 | |
| Honokiol SCHEMBL133034 | 0.82 | GABRA1 (1.00) | AKR1B1GABRA1GABRB2CNR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140756-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040532-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-13 | — | — | WO | disclosed |