Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971698 | 0.96 | MAPT (0.38) | MAPTKMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL5549293 | 0.93 | MAPT (0.39) | MAPTKMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL13005296 | 0.91 | MAPT (0.42) | MAPTKMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7777302 | 0.91 | DHODH (0.37) | MAPTKMT2AMAPK1ALDH1A1RAB9A | |
| SCHEMBL7785460 | 0.89 | MAPT (0.39) | MAPTKMT2AMAPK1L3MBTL1RAB9A | |
| SCHEMBL5550993 | 0.89 | MAPT (0.38) | MAPTKMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL4798246 | 0.89 | PLA2G2A (0.41) | MAPTKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL15693690 | 0.88 | DHODH (0.35) | MAPTKMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL15693594 | 0.87 | NR4A2 (0.34) | MAPTKMT2AMAPK1ALDH1A1RAB9A | |
| SCHEMBL5551024 | 0.87 | KMT2A (0.42) | MAPTKMT2AMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140892-A1 | PHOTOCHROMIC SUBSTIITUTED 2H-NAPHTHO[1,2-B]PYRANS | JAMES ROBINSON LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001012619-A1 | RAPID FADING PHOTO-RESPONSIVE MATERIALS | JAMES ROBINSON LIMITED (GB) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000035902-A1 | PHOTOCHROMIC SUBSTITUTED 2H-NAPHTHO[1,2-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |