Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 2/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777302 | 0.90 | DHODH (0.37) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL7784131 | 0.89 | MAPT (0.39) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL5549293 | 0.89 | MAPT (0.39) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL6131938 | 0.89 | DHODH (0.40) | MAPTKMT2AMEN1PDE1APDE1B | |
| SCHEMBL7784037 | 0.87 | MAPT (0.38) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL891063 | 0.86 | LRP6 (0.33) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL6131929 | 0.86 | KMT2A (0.39) | NPC1KMT2AMEN1PDE1APDE1B | |
| SCHEMBL15693690 | 0.85 | DHODH (0.35) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL7473791 | 0.85 | NPC1 (0.33) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL12907868 | 0.85 | HTR6 (0.36) | MAPTRAB9ANPC1GFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140892-A1 | PHOTOCHROMIC SUBSTIITUTED 2H-NAPHTHO[1,2-B]PYRANS | JAMES ROBINSON LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035902-A1 | PHOTOCHROMIC SUBSTITUTED 2H-NAPHTHO[1,2-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |