Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.38 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793587 | 0.86 | MAP1LC3B (0.38) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL7789614 | 0.85 | LMNA (0.35) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL7794162 | 0.85 | TP53 (0.36) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL7784152 | 0.83 | LMNA (0.35) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL8517535 | 0.82 | LMNA (0.55) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL8517536 | 0.82 | LMNA (0.55) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL7789621 | 0.82 | BLM (0.39) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL7793428 | 0.78 | HSP90AB1 (0.37) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL7793526 | 0.78 | HSP90AB1 (0.36) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ | |
| SCHEMBL6870451 | 0.77 | LMNA (0.54) | LMNAMAP1LC3BMAP1LC3AHSP90AB1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906326-B1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | AVENTIS PHARMA SA (FR) | 2001-11-21 | — | — | EP | disclosed |