Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.53 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.53 |
| ▸ | POLQ | O75417 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517536 | 1.00 | LMNA (0.55) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6870451 | 0.93 | LMNA (0.54) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6870457 | 0.93 | LMNA (0.54) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL7784151 | 0.82 | LMNA (0.39) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6867191 | 0.79 | MAP1LC3B (0.53) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6867193 | 0.79 | MAP1LC3B (0.53) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6864425 | 0.79 | HSP90AB1 (0.51) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6864426 | 0.79 | HSP90AB1 (0.51) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6865632 | 0.79 | HSP90AB1 (0.48) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A | |
| SCHEMBL6865629 | 0.79 | HSP90AB1 (0.48) | LMNAHSP90AB1HSP90AA1MAP1LC3BMAP1LC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906326-A1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | HOECHST MARION ROUSSEL (FR) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997047634-A1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | HOECHST MARION ROUSSEL (FR) | 1997-12-18 | — | — | WO | disclosed |