⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784276 | 0.78 | HDAC3 (0.33) | — | |
| SCHEMBL23601634 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL131675 | 0.74 | TBXA2R (0.46) | — | |
| SCHEMBL7784290 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL7784282 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL34468007 | 0.71 | TSHR (0.47) | — | |
| SCHEMBL867192 | 0.70 | RAB9A (0.54) | — | |
| SCHEMBL24632341 | 0.69 | TTR (0.37) | — | |
| Methacrylic Acid SCHEMBL8964171 | 0.69 | MAPT (0.45) | — | |
| SCHEMBL15239093 | 0.69 | PRMT5 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710475-B1 | High refractive index and/or radio-opaque resins systems | ABONETICS LTD (GB) | 2001-11-21 | — | — | EP | claimed |
| US-5679710-A | DENTAL COMPOSITES | LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1997-10-21 | — | — | US | claimed |
| EP-0710475-A1 | High refractive index and/or radio-opaque resins systems | THE LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1996-05-08 | — | — | EP | claimed |
| EP-0710475-B1 | High refractive index and/or radio-opaque resins systems | ABONETICS LTD (GB) | 2001-11-21 | — | — | EP | disclosed |
| EP-0684222-B1 | Novel (meth)acrylate monomers and denture base compositions prepared therefrom | ABONETICS LTD (GB) | 1998-10-14 | — | — | EP | disclosed |
| US-5679710-A | DENTAL COMPOSITES | LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0710475-A1 | High refractive index and/or radio-opaque resins systems | THE LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1996-05-08 | — | — | EP | disclosed |
| EP-0684222-A1 | Novel (meth)acrylate monomers and denture base compositions prepared therefrom | THE LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1995-11-29 | — | — | EP | disclosed |