Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131675 | 0.94 | TBXA2R (0.46) | MAPTLMNACYP2D6ADRB2ADRB1 | |
| Methacrylic Acid SCHEMBL28914843 | 0.87 | LMNA (0.57) | MAPTLMNAMTNR1AMTNR1BCYP2D6 | |
| SCHEMBL378569 | 0.83 | ADRB2 (0.52) | MAPTADRB2ADRB1ADRB3NPSR1 | |
| SCHEMBL15239093 | 0.83 | PRMT5 (0.46) | — | |
| SCHEMBL867192 | 0.81 | RAB9A (0.54) | MAPTPOLB | |
| SCHEMBL2204843 | 0.80 | TBXA2R (0.39) | MAPTLMNACYP2D6ADRB2ADRB1 | |
| SCHEMBL183191 | 0.79 | LMNA (0.49) | MAPTLMNAMTNR1AMTNR1BCYP2D6 | |
| SCHEMBL27608431 | 0.77 | LMNA (0.47) | MAPTLMNAMTNR1AMTNR1BCYP2D6 | |
| Formaldehyde SCHEMBL28047211 | 0.77 | POLB (0.48) | MAPTLMNAMTNR1AMTNR1BCYP2D6 | |
| SCHEMBL11040659 | 0.77 | LMNA (0.50) | MAPTLMNAMTNR1AMTNR1BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523358-A | REACTING POLYOLEFIN WITH ETHYLENICALLY UNSATURATED COMPOUND IN THE PRESENCE OF FREE RADICAL INITIATOR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0370753-B1 | Modified polyolefin particles and process for preparation thereof | MITSUI PETROCHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |