Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 10/20 | 1.00 |
| ▸ | NQO2 | P16083 | 7/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779922 | 0.91 | MTNR1A (0.83) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7784332 | 0.88 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7785010 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7784807 | 0.80 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7779907 | 0.79 | NQO2 (0.65) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8349133 | 0.77 | NQO2 (0.62) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL30589884 | 0.77 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL1289437 | 0.77 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7820683 | 0.76 | NQO2 (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL14613213 | 0.75 | MPO (0.59) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922771-A | MELATONIN RECEPTOR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-13 | — | — | US | claimed |
| EP-0848699-A1 | BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-06-24 | — | — | EP | claimed |
| WO-1997005098-A1 | BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-13 | — | — | WO | claimed |
| EP-0848699-B1 | BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5922771-A | MELATONIN RECEPTOR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0848699-A1 | BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997005098-A1 | BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-13 | — | — | WO | disclosed |