Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816176 | 0.77 | NOTUM (0.37) | NOTUMGPBAR1CES2VNN1 | |
| SCHEMBL6816180 | 0.77 | NOTUM (0.37) | NOTUMGPBAR1CES2VNN1 | |
| SCHEMBL27470801 | 0.74 | NOTUM (0.38) | NOTUMGPBAR1CES2VNN1 | |
| SCHEMBL7785667 | 0.73 | TAS1R3 (0.38) | NOTUMVNN1 | |
| SCHEMBL31749401 | 0.67 | NOTUM (0.68) | NOTUMCES2VNN1 | |
| SCHEMBL16958698 | 0.67 | CES2 (0.45) | NOTUMGPBAR1CES2VNN1 | |
| SCHEMBL7872121 | 0.67 | CES2 (0.42) | CES2 | |
| SCHEMBL6819613 | 0.66 | CES2 (0.45) | NOTUMCES2 | |
| SCHEMBL16957229 | 0.66 | CES2 (0.43) | NOTUMGPBAR1CES2VNN1 | |
| SCHEMBL15113096 | 0.66 | CES2 (0.43) | NOTUMGPBAR1CES2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |