Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 6/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 6/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 3/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814822 | 0.78 | NPFFR2 (0.42) | TAS1R3TAS1R1TAS1R2PTPN7DUSP3 | |
| SCHEMBL6814827 | 0.78 | NPFFR2 (0.42) | TAS1R3TAS1R1TAS1R2PTPN7DUSP3 | |
| SCHEMBL7784450 | 0.76 | PDE2A (0.38) | IDO1 | |
| SCHEMBL27472637 | 0.74 | PTPN7 (0.39) | TAS1R3TAS1R1TAS1R2PTPN7DUSP3 | |
| SCHEMBL7784407 | 0.73 | NOTUM (0.33) | NOTUMVNN1 | |
| SCHEMBL7872121 | 0.69 | CES2 (0.42) | — | |
| SCHEMBL14012580 | 0.68 | NOTUM (0.64) | TAS1R3TAS1R1TAS1R2HDAC8KCNQ3 | |
| SCHEMBL22561756 | 0.68 | NOTUM (0.47) | TAS1R3TAS1R1TAS1R2PTPN7DUSP3 | |
| SCHEMBL752590 | 0.68 | NOTUM (0.64) | TAS1R3TAS1R1TAS1R2HDAC8KCNQ3 | |
| SCHEMBL7847467 | 0.68 | GAA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6255349-B1 | PREVENTION REPRODUCTION; VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-03 | — | — | US | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |