Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
| ▸ | TNKS | O95271 | 4/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.55 |
| ▸ | PARP1 | P09874 | 3/20 | 0.55 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.55 |
| ▸ | WNT3A | P56704 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783581 | 0.81 | TNKS2 (0.70) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL30870677 | 0.79 | TNKS2 (0.75) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL7783531 | 0.75 | TNKS (0.60) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL7776852 | 0.74 | TNKS2 (0.73) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL7782072 | 0.73 | TNKS2 (0.71) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL30870720 | 0.71 | TNKS2 (0.60) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL30870640 | 0.71 | TNKS2 (0.60) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL14385545 | 0.71 | RNASEL (1.00) | RNASELSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL30870678 | 0.71 | TNKS2 (0.57) | TNKSTNKS2PARP1PARP3PARP2 | |
| SCHEMBL7783488 | 0.71 | TNKS2 (1.00) | TNKSTNKS2PARP1PARP3PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |