Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782854 | 0.89 | PTGDR2 (0.32) | PTGDR2AKR1B1MAPTSMN1; SMN2HTT | |
| SCHEMBL7784740 | 0.79 | PTGDR2 (0.36) | PTGDR2AKR1B1MAPTSMN1; SMN2HTT | |
| SCHEMBL7784902 | 0.78 | SMN1; SMN2 (0.34) | PTGDR2AKR1B1MAPTSMN1; SMN2HTT | |
| SCHEMBL7784930 | 0.76 | — | — | |
| SCHEMBL8664041 | 0.76 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL9220849 | 0.75 | MAPK14 (0.33) | MAPTNR1H2NR1H3CYP19A1 | |
| SCHEMBL5812558 | 0.75 | RXFP1 (0.36) | MAPTHTTNPSR1MEN1KMT2A | |
| SCHEMBL8799002 | 0.72 | MEN1 (0.34) | MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL7778321 | 0.72 | PTGDR2 (0.35) | PTGDR2AKR1B1HTTMEN1KMT2A | |
| SCHEMBL8986696 | 0.72 | MEN1 (0.36) | MAPTSMN1; SMN2XBP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |