Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780576 | 0.89 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7795354 | 0.89 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7802013 | 0.89 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7802211 | 0.89 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7795396 | 0.89 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| Hydrochloric Acid SCHEMBL7801297 | 0.89 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7801958 | 0.88 | MEN1 (0.39) | MEN1KMT2APOLBMAPKAPK2THRA | |
| SCHEMBL7789041 | 0.87 | KMT2A (0.36) | MEN1KMT2APOLBMAPKAPK2MAPT | |
| SCHEMBL7802163 | 0.85 | CXCR2 (0.39) | MEN1KMT2ACXCR2MAPTGAA | |
| SCHEMBL7801234 | 0.84 | THRA (0.36) | MEN1KMT2APOLBTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |