Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785017 | 0.85 | MEN1 (0.39) | CXCR2LPAR1MEN1KMT2AGAA | |
| SCHEMBL7805393 | 0.82 | CXCR2 (0.40) | CXCR2MEN1KMT2A | |
| SCHEMBL7795412 | 0.82 | CXCR2 (0.40) | CXCR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7803652 | 0.82 | CXCR2 (0.39) | CXCR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7795371 | 0.81 | CXCR2 (0.39) | CXCR2MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL7801488 | 0.80 | ALDH1A1 (0.49) | CXCR2KMT2AGAAKDM4ELMNA | |
| SCHEMBL7801773 | 0.80 | ALDH1A1 (0.49) | CXCR2KMT2AGAAKDM4ELMNA | |
| SCHEMBL7785410 | 0.80 | GAA (0.37) | CXCR2MEN1KMT2AGAAMAPT | |
| Hydrochloric Acid SCHEMBL7805684 | 0.80 | ALDH1A1 (0.48) | CXCR2KMT2AGAAKDM4ELMNA | |
| SCHEMBL7801234 | 0.80 | THRA (0.36) | CXCR2MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |