Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.37 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 3/20 | 0.34 |
| ▸ | AKT1 | P31749 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | PRKCG | P05129 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801234 | 0.91 | THRA (0.36) | MEN1KMT2APOLBCXCR2LMNA | |
| SCHEMBL7801984 | 0.89 | CXCR2 (0.36) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| SCHEMBL7785017 | 0.88 | MEN1 (0.39) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| SCHEMBL7780084 | 0.87 | MAPKAPK2 (0.38) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| Hydrochloric Acid SCHEMBL7795516 | 0.84 | THRA (0.37) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| SCHEMBL7795354 | 0.84 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| SCHEMBL7780576 | 0.84 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| SCHEMBL7802013 | 0.84 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| Hydrochloric Acid SCHEMBL7801297 | 0.83 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2CXCR2 | |
| Hydrochloric Acid SCHEMBL7802211 | 0.83 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |