Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363419 | 0.94 | — | — | |
| Water SCHEMBL10699759 | 0.91 | — | — | |
| SCHEMBL320485 | 0.84 | LDHA (0.61) | LDHASRRMMP12LMNAALKBH5 | |
| SCHEMBL320091 | 0.84 | LDHA (0.61) | LDHASRRMMP12LMNAALKBH5 | |
| SCHEMBL9971728 | 0.84 | — | — | |
| SCHEMBL2184678 | 0.80 | LDHA (0.67) | LDHASRRMMP12LMNAALKBH5 | |
| SCHEMBL28522 | 0.80 | LDHA (0.67) | LDHASRRMMP12LMNAALKBH5 | |
| Lindane SCHEMBL8746980 | 0.79 | LDHA (0.36) | LDHASRR | |
| SCHEMBL15422862 | 0.77 | LDHA (0.61) | LDHASRRMMP12LMNAALKBH5 | |
| SCHEMBL11603188 | 0.77 | LDHA (0.61) | LDHASRRMMP12LMNAALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141373-A1 | METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF 3,5-DIOXOCARBOXYLIC ACIDS, THEIR SALTS AND THEIR ESTERS | FORSCHUNGSZENTRUM JÜLICH GMBH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000036134-A1 | METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF 3,5-DIOXOCARBOXYLIC ACIDS, THEIR SALTS AND THEIR ESTERS | Forschungszentrum Jülich GmbH (DE) | 2000-06-22 | — | — | WO | disclosed |