Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 3/20 | 0.36 |
| ▸ | GALR1 | P47211 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785626 | 0.90 | MEN1 (0.41) | MEN1KMT2APOLBKLK7KLKB1 | |
| SCHEMBL7780087 | 0.84 | KMT2A (0.45) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7785096 | 0.81 | MEN1 (0.40) | MEN1KMT2APOLBGALR2GALR1 | |
| SCHEMBL7787472 | 0.81 | MEN1 (0.40) | MEN1KMT2APOLBGALR2GALR1 | |
| SCHEMBL7789113 | 0.81 | KMT2A (0.44) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL7785061 | 0.80 | KMT2A (0.44) | MEN1KMT2APOLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7803820 | 0.80 | RAB9A (0.45) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7784907 | 0.80 | SIGMAR1 (0.44) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7785547 | 0.78 | SLC6A4 (0.42) | MEN1KMT2AKLK7CTSLCTSS | |
| SCHEMBL7784885 | 0.78 | KMT2A (0.43) | MEN1KMT2APOLBMAPKAPK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |