Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785626 | 0.82 | MEN1 (0.41) | KLK7HTTCTSLCTSSKDM4E | |
| SCHEMBL7780342 | 0.80 | KMT2A (0.54) | HTTTDP1MEN1LMNAKMT2A | |
| SCHEMBL7785243 | 0.78 | MEN1 (0.41) | KLK7HTTCTSLCTSSKDM4E | |
| SCHEMBL27553437 | 0.77 | SLC6A2 (0.46) | SLC6A4SLC6A3SLC6A2HTTKDM4E | |
| SCHEMBL7785199 | 0.77 | SLC6A2 (0.46) | SLC6A4SLC6A3SLC6A2HTTKDM4E | |
| SCHEMBL7784935 | 0.77 | SLC6A2 (0.46) | SLC6A4SLC6A3SLC6A2HTTKDM4E | |
| SCHEMBL17065063 | 0.77 | KLKB1 (0.47) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL31067562 | 0.77 | KLKB1 (0.47) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7785046 | 0.77 | TDP1 (0.49) | HTTTDP1KDM4EMEN1KMT2A | |
| SCHEMBL7785644 | 0.75 | RAB9A (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |