SCHEMBL7785449

SCHEMBL7785449

C#CCCC#CN(C#CCCC#C)C(=O)Cl

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27352986 0.71
SCHEMBL8945457 0.68 ALDH1A1 (0.32) KDM4EALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL8945449 0.68 MAPT (0.39) KDM4EALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL8034974 0.65 CYP1A2 (0.30) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL1401585 0.64 KDM4E (0.32) KDM4EALDH1A1HPGDCYP1A2CYP2D6
Bromide SCHEMBL28475231 0.62 KDM4E (0.31) KDM4EALDH1A1HPGD
SCHEMBL103100 0.61
SCHEMBL379206 0.61 CYP1A2 (0.43) KDM4EALDH1A1HPGDCYP1A2CYP2D6
SCHEMBL1028327 0.59
Carbamic Acid SCHEMBL16013788 0.59 ACHE (0.47) KDM4EALDH1A1HPGDCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1144392-A1 NOVEL TETRAZOLINONE DERIVATIVES NIHON BAYER AGROCHEM K.K. (JP) 2001-10-17 EP disclosed
WO-2000040568-A1 NOVEL TETRAZOLINONE DERIVATIVES NIHON BAYER AGROCHEM K.K. (DE) 2000-07-13 WO disclosed
EP-0820994-A1 Tetrazolinones as herbicides and intermediates NIHON BAYER AGROCHEM K.K. (JP) 1998-01-28 EP disclosed