Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.62 |
| ▸ | CNR2 | P34972 | 6/20 | 0.62 |
| ▸ | CNR1 | P21554 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978632 | 0.87 | GABRA1 (0.72) | GABRA1GABRB2CNR2CNR1MEN1 | |
| SCHEMBL7747447 | 0.84 | GABRA1 (0.77) | GABRA1GABRB2CNR2CNR1MEN1 | |
| Randaiol SCHEMBL24922822 | 0.82 | GABRA1 (0.85) | GABRA1GABRB2CNR2CNR1MEN1 | |
| Randaiol SCHEMBL30114878 | 0.82 | GABRA1 (0.85) | GABRA1GABRB2CNR2CNR1MEN1 | |
| SCHEMBL7785448 | 0.80 | GABRA1 (0.76) | GABRA1GABRB2CNR2CNR1MEN1 | |
| Magnolol SCHEMBL23119980 | 0.79 | GABRA1 (0.85) | GABRA1GABRB2CNR2CNR1MEN1 | |
| Magnolol SCHEMBL29649179 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2CNR2CNR1MEN1 | |
| Magnolol SCHEMBL29538482 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2CNR2CNR1MEN1 | |
| Magnolol SCHEMBL132477 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2CNR2CNR1MEN1 | |
| Magnolol SCHEMBL5511922 | 0.79 | GABRA1 (0.72) | GABRA1GABRB2CNR2CNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140756-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040532-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-13 | — | — | WO | disclosed |