Magnolol

Magnolol

SCHEMBL29538482

C=CCc1ccc(O)c(-c2cc(CC=C)ccc2O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 10/20 1.00
GABRB2 P47870 10/20 1.00
CNR2 P34972 5/20 1.00
CNR1 P21554 4/20 1.00
ALDH1A1 P00352 3/20 1.00
MEN1 O00255 2/20 1.00
GAA P10253 2/20 1.00
MAPT P10636 2/20 1.00
KMT2A Q03164 2/20 1.00
PPARG P37231 2/20 1.00
PPARD Q03181 2/20 1.00
KDM4E B2RXH2 1/20 1.00
ALDH2 P05091 1/20 1.00
AKR1B1 P15121 1/20 1.00
HPGD P15428 1/20 1.00
NPSR1 Q6W5P4 1/20 1.00
TNKS O95271 1/20 0.79
PARP1 P09874 1/20 0.79
XDH P47989 1/20 0.73
ALOX5 P09917 6/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Magnolol SCHEMBL132477 1.00 GABRA1 (1.00) GABRA1GABRB2CNR2CNR1ALDH1A1
Magnolol SCHEMBL29649179 1.00 GABRA1 (1.00) GABRA1GABRB2CNR2CNR1ALDH1A1
Randaiol SCHEMBL24922822 0.92 GABRA1 (0.85) GABRA1GABRB2CNR2CNR1ALDH1A1
Randaiol SCHEMBL30114878 0.92 GABRA1 (0.85) GABRA1GABRB2CNR2CNR1ALDH1A1
Magnolol SCHEMBL23119980 0.92 GABRA1 (0.85) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL30262895 0.92 TNKS (0.87) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL23143161 0.91 GABRA1 (0.82) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL20153052 0.91 GABRA1 (0.82) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL21076210 0.89 GABRA1 (0.79) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL14368297 0.89 GABRA1 (0.79) GABRA1GABRB2CNR2CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12161686-B2 Natural preservatives and antimicrobial agents, including compositions thereof UNIGEN, INC. (US) 2024-12-10 US claimed
US-20230131719-A1 Natural Preservatives and Antimicrobial Agents, Including Compositions Thereof UNIGEN, INC. (US) 2023-04-27 US claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
US-11529384-B2 Natural preservatives and antimicrobial agents, including compositions thereof UNIGEN, INC. (US) 2022-12-20 US claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20250099526-A1 Natural Preservatives and Antimicrobial Agents, Including Compositions Thereof UNIGEN, INC. (US) 2025-03-27 US disclosed
US-12161686-B2 Natural preservatives and antimicrobial agents, including compositions thereof UNIGEN, INC. (US) 2024-12-10 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
EP-4421109-A1 SIDE-CHAIN FUNCTIONALIZED POLYARYLETHERSULFONES AND THEIR USE IN CHROMATOGRAPHY APPLICATIONS Solvay Specialty Polymers USA, LLC (US) 2024-08-28 EP disclosed
US-20240050943-A1 MULTI-VOLUME MICROCHAMBER-BASED MICROFLUIDIC PLATFORM AND USE THEREOF CORNELL UNIVERSITY 2024-02-15 US disclosed
US-20230131719-A1 Natural Preservatives and Antimicrobial Agents, Including Compositions Thereof UNIGEN, INC. (US) 2023-04-27 US disclosed
CN-115768452-A Coriolus versicolor extract for treating vaginal or cervical disorders caused by infectious pathogens 伊比利亚护理健康有限公司 2023-03-07 CN disclosed
US-11529384-B2 Natural preservatives and antimicrobial agents, including compositions thereof UNIGEN, INC. (US) 2022-12-20 US disclosed
CN-113207878-B Application of magnolol as agricultural bactericide 江苏省中国科学院植物研究所 2022-11-29 CN disclosed
CN-109641183-B Prevention and treatment of vascular calcification and cardiovascular/related diseases 顶峰创新实验室有限公司 2022-07-12 CN disclosed
WO-2022140585-A1 GRADIENT-BASED MICROFLUIDIC CIRCUIT, DEVICE, AND METHOD FOR PERFORMING AN ASSAY CORNELL UNIVERSITY (US) 2022-06-30 WO disclosed
WO-2022140599-A1 MULTI-VOLUME MICROCHAMBER-BASED MICROFLUIDIC PLATFORM AND USE THEREOF CORNELL UNIVERSITY (US) 2022-06-30 WO disclosed
CN-113197214-B Application of tetrandrine as agricultural bactericide 江苏省中国科学院植物研究所 2022-04-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B GABRA1 3882/4885GABRB2 3870/4885CNR2 2365/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 GABRA1 4110/4885GABRB2 4241/4885CNR2 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.