Magnolol

Magnolol

SCHEMBL132477

C=CCc1ccc(O)c(-c2cc(CC=C)ccc2O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 10/20 1.00
GABRB2 P47870 10/20 1.00
CNR2 P34972 5/20 1.00
CNR1 P21554 4/20 1.00
ALDH1A1 P00352 3/20 1.00
MEN1 O00255 2/20 1.00
GAA P10253 2/20 1.00
MAPT P10636 2/20 1.00
KMT2A Q03164 2/20 1.00
PPARG P37231 2/20 1.00
PPARD Q03181 2/20 1.00
KDM4E B2RXH2 1/20 1.00
ALDH2 P05091 1/20 1.00
AKR1B1 P15121 1/20 1.00
HPGD P15428 1/20 1.00
NPSR1 Q6W5P4 1/20 1.00
TNKS O95271 1/20 0.79
PARP1 P09874 1/20 0.79
XDH P47989 1/20 0.73
ALOX5 P09917 6/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Magnolol SCHEMBL29649179 1.00 GABRA1 (1.00) GABRA1GABRB2CNR2CNR1ALDH1A1
Magnolol SCHEMBL29538482 1.00 GABRA1 (1.00) GABRA1GABRB2CNR2CNR1ALDH1A1
Randaiol SCHEMBL24922822 0.92 GABRA1 (0.85) GABRA1GABRB2CNR2CNR1ALDH1A1
Randaiol SCHEMBL30114878 0.92 GABRA1 (0.85) GABRA1GABRB2CNR2CNR1ALDH1A1
Magnolol SCHEMBL23119980 0.92 GABRA1 (0.85) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL30262895 0.92 TNKS (0.87) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL23143161 0.91 GABRA1 (0.82) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL20153052 0.91 GABRA1 (0.82) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL21076210 0.89 GABRA1 (0.79) GABRA1GABRB2CNR2CNR1ALDH1A1
SCHEMBL14368297 0.89 GABRA1 (0.79) GABRA1GABRB2CNR2CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9129 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748368-A1 COMPOSITION FOR ORAL HYGIENE PRODUCTS COMPRISING N-CETYLPYRIDINIUM CHLORIDE, A FLAVONOID AND A POLYMER Curaden AG (CH) 2026-05-27 EP claimed
CN-122075567-A A composition containing herba Silybi Mariani extract and Akk bacteria 2026-05-26 CN claimed
CN-122075799-A Hydrogel for cartilage repair and preparation method thereof 2026-05-26 CN claimed
CN-122080606-A Allyl polyarylester modified bismaleimide resin and preparation method and application thereof 2026-05-26 CN claimed
CN-117820287-B Magnolol derivative, and preparation method and application thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN claimed
CN-118305065-B Aluminum alloy with surface loaded with bio-based antibacterial components and preparation method thereof SHANDONG CHUANGXIN PRECISION TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
CN-122011324-A Polyurethane with sound absorption layer and buffer layer coupled and application of polyurethane in noise reduction earmuffs 广东金海纳实业有限公司 2026-05-12 CN claimed
CN-122005674-A Formula for treating nocardia of fish and preparation method thereof 广西壮族自治区水产科学研究院(广西壮族自治区渔业病害防治环境监测和质量检验中心、广西壮族自治区水生野生动物救护中心) 2026-05-12 CN claimed
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 EP claimed
WO-2001009118-A2 DITHIOLTHIONE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS AND FOR MEMORY ENHANCEMENT PRENDERGAST PATRICK T (IE) 2001-02-08 WO claimed
CN-1270168-A Magnolol series of compounds, synthesizing process thereof, and medicinal composition using same as active component LI ANRONG (CN) 2000-10-18 CN claimed
CN-1191130-A Anti-AIDS virus, anti-Treponema pallidum, anti-gonococcus, anti-candida albicans and anti-trichomonas natural drug LEI XUEJUN (CN) 1998-08-26 CN claimed
CN-1189365-A Medicine for preventing Aids virus, treponema pallidum, neisseria gonorrhoeae and trichomonad LEI XUEJUN (CN) 1998-08-05 CN claimed
EP-0382213-B1 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMA CO LTD (JP) 1995-05-10 EP claimed
US-5135746-A Tannins, resin glycosides, magnolol combined with ionophore antibiotics, oral administration TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-04 US claimed
EP-0395294-A2 Control of protozoal disease Takeda Chemical Industries, Ltd. (JP) 1990-10-31 EP claimed
CN-1044807-A Neurocyte sex change reparation or protective material are with composition and the preparation method that is used for the benzene derivative of said composition OTSUKA PHARMA CO LTD (JP) 1990-08-22 CN claimed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP claimed
CN-85103128-A The extracting method of magnolol and Honokiol 1987-02-04 CN claimed