Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780620 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7785104 | 0.88 | GAA (0.46) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7785523 | 0.88 | MAPT (0.40) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7787701 | 0.86 | MAPK1 (0.45) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7780352 | 0.86 | MAPK1 (0.45) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7787867 | 0.86 | MAPK1 (0.45) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7785020 | 0.82 | GAA (0.40) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7785657 | 0.81 | SMN1; SMN2 (0.37) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7785707 | 0.80 | MAPT (0.43) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL7785072 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |