Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | EEF2K | O00418 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.41 |
| ▸ | ITGAV | P06756 | 8/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785619 | 0.85 | ATM (0.42) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7786192 | 0.85 | EEF2K (0.52) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7781105 | 0.85 | EEF2K (0.47) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7790163 | 0.85 | ALDH1A1 (0.46) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7785625 | 0.85 | EEF2K (0.41) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7785635 | 0.84 | ATM (0.52) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7789956 | 0.83 | EEF2K (0.39) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7187004 | 0.83 | MAPT (0.48) | ATML3MBTL1EEF2KALDH1A1ITGB3 | |
| SCHEMBL7788768 | 0.82 | ATM (0.40) | ATML3MBTL1ALDH1A1ITGB3 | |
| SCHEMBL7194899 | 0.81 | ITGB3 (0.44) | ALDH1A1ITGB3ITGAVKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |