Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EEF2K | O00418 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786192 | 0.89 | EEF2K (0.52) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL7785635 | 0.87 | ATM (0.52) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL7785658 | 0.87 | LMNA (0.44) | ALDH1A1KMT2AHCRTR1HCRTR2ITGB3 | |
| SCHEMBL7781105 | 0.85 | EEF2K (0.47) | ALDH1A1ATML3MBTL1EEF2KITGB3 | |
| SCHEMBL7785590 | 0.85 | ATM (0.42) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL7187004 | 0.84 | MAPT (0.48) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL7785607 | 0.84 | LMNA (0.46) | ALDH1A1KMT2AITGB3ITGAVMEN1 | |
| SCHEMBL7785619 | 0.83 | ATM (0.42) | ALDH1A1ATML3MBTL1EEF2KITGB3 | |
| SCHEMBL7785625 | 0.82 | EEF2K (0.41) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL7789956 | 0.81 | EEF2K (0.39) | ALDH1A1ATML3MBTL1KMT2AEEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |