Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639011 | 0.83 | GAA (0.43) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL13434059 | 0.82 | TSHR (0.54) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL22732403 | 0.76 | ALDH1A1 (0.58) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL17685349 | 0.76 | ALDH1A1 (0.58) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL16000091 | 0.76 | KDM4E (0.48) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL6642094 | 0.75 | GAA (0.47) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL10334730 | 0.75 | KCNA5 (0.46) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL5402590 | 0.75 | CRHBP (0.54) | TSHRKDM4ECYP3A4LMNAESR1 | |
| SCHEMBL3292596 | 0.75 | SLC6A3 (0.43) | TSHRKDM4ECYP3A4LMNAABCB11 | |
| SCHEMBL112007 | 0.75 | CYP3A4 (0.43) | TSHRKDM4ECYP3A4LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626406-B1 | Process for preparing thermoplastic polyesters possessing high stability in the molten state | GROUP S R L P (IT) | 2001-10-31 | — | — | EP | disclosed |
| EP-0626406-A2 | Thermoplastic polyesters possessing high stability in the molten state | ENICHEM S.p.A. (IT) | 1994-11-30 | — | — | EP | disclosed |