Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031257 | 0.87 | ALDH1A1 (0.71) | MAPTRECQLATMGAANPC1 | |
| SCHEMBL28216488 | 0.86 | KCNK3 (0.62) | RECQLGAANPC1RAB9AL3MBTL1 | |
| SCHEMBL474709 | 0.79 | KMT2A (0.70) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL209624 | 0.79 | ATM (0.67) | ATML3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL20491276 | 0.79 | SMN1; SMN2 (0.63) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL29493316 | 0.78 | GAA (0.68) | MAPTGAANPC1RAB9AL3MBTL1 | |
| SCHEMBL687148 | 0.78 | GAA (0.68) | MAPTGAANPC1RAB9AL3MBTL1 | |
| SCHEMBL31022695 | 0.76 | MEN1 (0.62) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL29536454 | 0.76 | GAA (0.66) | MAPTGAANPC1RAB9AL3MBTL1 | |
| SCHEMBL758991 | 0.76 | MEN1 (0.62) | MAPTNPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |