Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781202 | 0.82 | DRD2 (0.44) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL7790200 | 0.78 | DRD2 (0.53) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL7790205 | 0.78 | DRD2 (0.53) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL7785692 | 0.77 | DRD2 (0.53) | DRD2DRD3DRD4 | |
| SCHEMBL7790219 | 0.73 | DRD2 (0.43) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL7781192 | 0.71 | DRD2 (0.44) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL7788385 | 0.70 | DRD2 (0.46) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL7781213 | 0.69 | DRD2 (0.46) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL7785770 | 0.67 | DRD2 (0.46) | DRD2DRD3DRD4 | |
| SCHEMBL7785764 | 0.67 | DRD2 (0.46) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717620-B1 | SUBSTITUTED 2-AMINOTETRALINS | DISCOVERY THERAPEUTICS INC (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5382596-A | Useful for alleviating Parkinsonism, glaucoma, hyperprolactinemia and for inducing weight loss in mammals | WHITBY RESEARCH, INC. (US) | 1995-01-17 | — | — | US | disclosed |