SCHEMBL7785945

SCHEMBL7785945

C=CC(=O)NCc1ccccc1S(=O)(=O)NS(=O)(=O)c1ccccc1OC

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
ALDH1A1 P00352 5/20 0.43
HPGD P15428 4/20 0.43
HSD17B10 Q99714 2/20 0.43
ITGAV P06756 1/20 0.42
MEN1 O00255 3/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
BLM P54132 1/20 0.42
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NAMPT P43490 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HDAC1 Q13547 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765637 0.82 HPGD (0.61) KMT2AALDH1A1HPGDMEN1POLB
SCHEMBL3250189 0.81 TGM2 (0.41) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL393748 0.79 GAA (0.40) KMT2AALDH1A1POLBNAMPTGAA
SCHEMBL397606 0.79 CA12 (0.42) KMT2AALDH1A1GAA
SCHEMBL7751009 0.78 OPRM1 (0.40) KMT2AALDH1A1HPGDHSD17B10NPSR1
SCHEMBL396499 0.77 CA12 (0.52) KMT2APOLBGAASMN1; SMN2
SCHEMBL28544730 0.76 TGM2 (0.44) KMT2AALDH1A1NPC1RAB9AGAA
SCHEMBL397222 0.76 TGM2 (0.44) KMT2AALDH1A1HPGDMEN1POLB
SCHEMBL7751036 0.76 ATM (0.40) KMT2AALDH1A1HPGDHSD17B10MEN1
SCHEMBL396012 0.76 ALDH1A1 (0.39) KMT2AALDH1A1HPGDHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed