Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785978 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBAPAF1CASRCYP1A2 | |
| SCHEMBL29560 | 0.77 | SMN1; SMN2 (0.76) | SMN1; SMN2POLBAPAF1CASRCYP1A2 | |
| SCHEMBL197618 | 0.77 | LMNA (0.52) | CYP2D6ADRB2ADRB1ALDH1A1MAPK1 | |
| SCHEMBL29398319 | 0.77 | LMNA (0.52) | CYP2D6ADRB2ADRB1ALDH1A1MAPK1 | |
| SCHEMBL24732 | 0.77 | LMNA (0.52) | CYP2D6ADRB2ADRB1ALDH1A1MAPK1 | |
| SCHEMBL24733 | 0.77 | LMNA (0.52) | CYP2D6ADRB2ADRB1ALDH1A1MAPK1 | |
| SCHEMBL79765 | 0.77 | SMN1; SMN2 (0.76) | SMN1; SMN2POLBAPAF1CASRCYP1A2 | |
| SCHEMBL774613 | 0.77 | SMN1; SMN2 (0.76) | SMN1; SMN2POLBAPAF1CASRCYP1A2 | |
| SCHEMBL29465008 | 0.77 | LMNA (0.52) | CYP2D6ADRB2ADRB1ALDH1A1MAPK1 | |
| SCHEMBL29501895 | 0.77 | LMNA (0.52) | CYP2D6ADRB2ADRB1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001072644-A | PRODUCTION OF OPTICALLY ACTIVE 2-CHLOROMANDELIC ACID AND PRODUCTION INTERMEDIATE | YAMAKAWA YAKUHIN KOGYO KK | 2001-03-21 | — | — | JP | disclosed |