Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.87 |
| ▸ | NPC1 | O15118 | 2/20 | 0.87 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | FGB | P02675 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496978 | 0.93 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4700188 | 0.87 | RAB9A (0.71) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL9181274 | 0.87 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL7970824 | 0.82 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL3862633 | 0.81 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL28792529 | 0.81 | RAB9A (0.63) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| 1,4-Dimethoxyanthraquinone SCHEMBL3417221 | 0.81 | MAPT (1.00) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL9264626 | 0.79 | MAPT (0.74) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL12253692 | 0.79 | RAB9A (0.76) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL29126288 | 0.78 | MAPT (0.66) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109700791-A | Hongmaoxinjian is preparing the application in anti-benign prostatic hyperplasis drug | 西安交通大学 | 2019-05-03 | — | — | CN | disclosed |
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0906268-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045397-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-04 | — | — | WO | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |