SCHEMBL7786188

SCHEMBL7786188

OCCCCO[Si](OCCCCO)(OCCCCO)OCCCCO

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LOX P28300 1/20 0.33
AOC3 Q16853 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14719693 0.97 LMNA (0.36) LOXAOC3SMN1; SMN2LMNATSHR
SCHEMBL988557 0.90 TSHR (0.32) TSHRALDH1A1MEN1KMT2AMAPK1
SCHEMBL2722072 0.87 SMN1; SMN2 (0.38) SMN1; SMN2LMNATSHRALDH1A1HSD17B10
1-Hexanol SCHEMBL7675083 0.85 LMNA (0.59) SMN1; SMN2LMNATSHRALDH1A1HSD17B10
Decanol SCHEMBL7661100 0.85 LMNA (0.59) SMN1; SMN2LMNATSHRALDH1A1HSD17B10
SCHEMBL2722135 0.84 SMN1; SMN2 (0.33) SMN1; SMN2LMNATSHRALDH1A1HSD17B10
SCHEMBL7784473 0.77 SMN1; SMN2 (0.36) LOXAOC3SMN1; SMN2LMNATSHR
SCHEMBL5963881 0.77 SMN1; SMN2 (0.36) LOXAOC3SMN1; SMN2LMNATSHR
SCHEMBL987278 0.76 TSHR (0.44) TSHRALDH1A1MEN1KMT2AMAPK1
SCHEMBL8688535 0.75 LMNA (0.39) LOXAOC3SMN1; SMN2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9751899-B2 Synthesis method of alkoxysilanes LAINE RICHARD M (US) 2017-09-05 US disclosed
US-9751899-B2 Synthesis method of alkoxysilanes LAINE RICHARD M (US) 2017-09-05 US disclosed
US-20160304540-A1 SYNTHESIS METHOD OF ALKOXYSILANES LAINE RICHARD M (US) 2016-10-20 US disclosed
US-20160304540-A1 SYNTHESIS METHOD OF ALKOXYSILANES LAINE RICHARD M (US) 2016-10-20 US disclosed
EP-0789053-B1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 2001-10-24 EP disclosed
EP-0789053-A1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 1997-08-13 EP disclosed
EP-0507178-A2 Stabilization of high temperature deformation resistant polycarbonate BAYER AG (DE) 1992-10-07 EP disclosed
US-4342681-A Use of organic silicon compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-03 US disclosed
EP-0019217-A1 Use of organic silicium compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for the stabilisation and brightening of polycarbonates free from phosphites and boric acid esters BAYER AG (DE) 1980-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304540-A1 SYNTHESIS METHOD OF ALKOXYSILANES SIK2, S1PR4, SGPL1 LOX 334/4885AOC3 383/4885SMN1; SMN2 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.