SCHEMBL2722072

SCHEMBL2722072

CCO[Si](OCC)(OCC)OCCCCO

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP4F2 P78329 3/20 0.34
CYP4A11 Q02928 3/20 0.34
ACHE P22303 6/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL21810755 0.90 SMN1; SMN2 (0.45) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A
SCHEMBL7786188 0.87 LOX (0.33) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A
SCHEMBL14719693 0.85 LMNA (0.36) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A
Decanol SCHEMBL7661100 0.84 LMNA (0.59) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A
1-Hexanol SCHEMBL7675083 0.84 LMNA (0.59) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A
SCHEMBL2006725 0.82 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ATSHRTHRB
Myristyl Alcohol SCHEMBL28578079 0.81 LMNA (0.62) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A
Butyl Alcohol SCHEMBL28094279 0.80 ALDH1A1 (0.58) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A
SCHEMBL17644808 0.80 THRB (0.35) MEN1KMT2ATSHRTHRBHTT
SCHEMBL10629447 0.80 THRB (0.35) MEN1KMT2ATSHRTHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120157575-A1 POLYMER COMPOSITION, RUBBER COMPOSITION, AND TIRE OBTAINED USING SAME BRIDGESTONE CORPORATION (JP) 2012-06-21 US disclosed
EP-2447318-A1 POLYMER COMPOSITION, RUBBER COMPOSITION, AND TIRE OBTAINED USING SAME Bridgestone Corporation (JP) 2012-05-02 EP disclosed