SCHEMBL7784473

SCHEMBL7784473

C[Si](OCCCCO)(OCCCCO)OCCCCO

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TSHR P16473 1/20 0.35
ACHE P22303 6/20 0.31
LOX P28300 1/20 0.31
AOC3 Q16853 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28086855 0.87 SMN1; SMN2 (0.32) SMN1; SMN2LMNAALDH1A1MEN1KMT2A
SCHEMBL5963881 0.83 SMN1; SMN2 (0.36) SMN1; SMN2LMNAALDH1A1MEN1KMT2A
SCHEMBL2255083 0.81 LMNA (0.39) SMN1; SMN2LMNAALDH1A1MEN1KMT2A
SCHEMBL8688500 0.81 LMNA (0.39) SMN1; SMN2LMNAALDH1A1MEN1KMT2A
SCHEMBL8688535 0.81 LMNA (0.39) SMN1; SMN2LMNAALDH1A1MEN1KMT2A
SCHEMBL1360843 0.79 TSHR (0.39) ALDH1A1MEN1KMT2ATSHR
SCHEMBL7786188 0.77 LOX (0.33) SMN1; SMN2LMNAALDH1A1MEN1KMT2A
SCHEMBL334934 0.75 DUT (0.38) SMN1; SMN2
SCHEMBL661810 0.74 THRB (0.39) ALDH1A1MEN1KMT2ATSHRTHRB
SCHEMBL3836906 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789053-B1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 2001-10-24 EP disclosed
US-5852138-A Stabilizer mixtures and their use in polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
EP-0789053-A1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 1997-08-13 EP disclosed
EP-0507178-A2 Stabilization of high temperature deformation resistant polycarbonate BAYER AG (DE) 1992-10-07 EP disclosed
US-4342681-A Use of organic silicon compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-03 US disclosed
EP-0019217-A1 Use of organic silicium compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for the stabilisation and brightening of polycarbonates free from phosphites and boric acid esters BAYER AG (DE) 1980-11-26 EP disclosed