Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 5/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGAV | P06756 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366667 | 0.87 | ITGB3 (0.60) | EEF2KITGB3ITGAV | |
| SCHEMBL7786198 | 0.87 | ITGB3 (0.49) | EEF2KITGB3ITGAVMEN1LMNA | |
| SCHEMBL7781109 | 0.87 | ITGB3 (0.49) | EEF2KITGB3ITGAVMEN1KMT2A | |
| SCHEMBL7781187 | 0.85 | GAA (0.47) | EEF2KITGB3GAAMEN1LMNA | |
| SCHEMBL7785592 | 0.83 | ITGB3 (0.49) | EEF2KITGB3ITGAVMEN1LMNA | |
| SCHEMBL7790169 | 0.83 | ITGB3 (0.49) | ITGB3ITGAVGAAMEN1LMNA | |
| SCHEMBL7785637 | 0.82 | ATM (0.50) | EEF2KITGB3ITGAVMAPT | |
| SCHEMBL7785621 | 0.82 | ITGB3 (0.48) | EEF2KITGB3ITGAVSLC1A3SLC1A2 | |
| SCHEMBL7785629 | 0.82 | ITGB3 (0.46) | EEF2KITGB3ITGAVMEN1LMNA | |
| SCHEMBL7789961 | 0.81 | ITGB3 (0.49) | EEF2KITGB3ITGAVMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |