Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.49 |
| ▸ | ITGAV | P06756 | 10/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366667 | 0.88 | ITGB3 (0.60) | ITGB3ITGAVPKMATML3MBTL1 | |
| SCHEMBL7786198 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVATML3MBTL1EEF2K | |
| SCHEMBL7781109 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVATML3MBTL1EEF2K | |
| SCHEMBL7790169 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVATMALDH1A1MEN1 | |
| SCHEMBL13715863 | 0.84 | PKM (0.46) | ITGB3ITGAVPKML3MBTL1ALDH1A1 | |
| SCHEMBL7785637 | 0.84 | ATM (0.50) | ITGB3ITGAVATML3MBTL1EEF2K | |
| SCHEMBL7785629 | 0.84 | ITGB3 (0.46) | ITGB3ITGAVEEF2KALDH1A1MEN1 | |
| SCHEMBL7785621 | 0.84 | ITGB3 (0.48) | ITGB3ITGAVATML3MBTL1EEF2K | |
| SCHEMBL7789961 | 0.84 | ITGB3 (0.49) | ITGB3ITGAVATML3MBTL1EEF2K | |
| SCHEMBL7786249 | 0.83 | EEF2K (0.50) | ITGB3ITGAVEEF2KMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |