Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | ITGAV | P06756 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | TCF4 | P15884 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786198 | 0.89 | ITGB3 (0.49) | ITGB3ITGAVMAPTALDH1A1LMNA | |
| SCHEMBL7785662 | 0.88 | MAPT (0.48) | ITGB3MAPTALDH1A1LMNAATM | |
| SCHEMBL7785637 | 0.87 | ATM (0.50) | ITGB3ITGAVMAPTALDH1A1ATM | |
| SCHEMBL6366667 | 0.87 | ITGB3 (0.60) | ITGB3ITGAVALDH1A1ATM | |
| SCHEMBL7781109 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVALDH1A1ATMKMT2A | |
| SCHEMBL7785592 | 0.85 | ITGB3 (0.49) | ITGB3ITGAVMAPTALDH1A1LMNA | |
| SCHEMBL7785609 | 0.85 | LMNA (0.45) | ITGB3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7187012 | 0.83 | MAPT (0.47) | ITGB3ITGAVMAPTALDH1A1LMNA | |
| SCHEMBL7786249 | 0.83 | EEF2K (0.50) | ITGB3ITGAVMAPTLMNAKMT2A | |
| SCHEMBL13715863 | 0.82 | PKM (0.46) | ITGB3ITGAVMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |