Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.62 |
| ▸ | ITGAV | P06756 | 15/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786259 | 1.00 | ITGB3 (0.62) | ITGB3ITGAVMTORHDAC3HDAC4 | |
| SCHEMBL7787963 | 0.81 | ITGB3 (0.53) | ITGB3ITGAV | |
| SCHEMBL7787965 | 0.81 | ITGB3 (0.53) | ITGB3ITGAV | |
| SCHEMBL7790192 | 0.81 | NAMPT (0.58) | ITGB3ITGAV | |
| SCHEMBL7785608 | 0.79 | NAMPT (0.57) | ITGB3ITGAV | |
| SCHEMBL5878743 | 0.77 | ITGB3 (1.00) | ITGB3ITGAVMTOR | |
| SCHEMBL5340097 | 0.75 | ITGB3 (0.88) | ITGB3ITGAVMTOR | |
| SCHEMBL5878235 | 0.73 | ITGB3 (0.89) | ITGB3ITGAVMTOR | |
| SCHEMBL24106585 | 0.73 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL5878242 | 0.72 | ITGB3 (0.65) | ITGB3ITGAVMTORHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |