Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586767 | 0.86 | PTPN1 (0.56) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL27744698 | 0.85 | CES2 (0.46) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL30634441 | 0.83 | PTPN1 (0.56) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL21462078 | 0.83 | PTPN1 (0.56) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL2097720 | 0.83 | CES2 (0.66) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL1960700 | 0.83 | PTPN1 (0.56) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL30006617 | 0.83 | PTPN1 (0.56) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL9526674 | 0.81 | PTPN1 (0.54) | PTPN1GSK3BCES2KDM4EALDH1A1 | |
| SCHEMBL422332 | 0.80 | ALDH1A1 (0.62) | CES2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3916517 | 0.79 | PTPN1 (0.56) | PTPN1GSK3BCES2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |