Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074635 | 0.86 | DRD2 (0.64) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL1193917 | 0.86 | DRD2 (0.64) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL2314625 | 0.82 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL30080716 | 0.82 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL9036478 | 0.82 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL30080714 | 0.82 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL2314632 | 0.82 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL27597995 | 0.82 | DRD2 (0.57) | DRD2DRD3ADRA1AHTR1AKDM4E | |
| SCHEMBL4617829 | 0.82 | DRD2 (0.77) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL6526368 | 0.81 | DRD2 (0.85) | DRD2DRD3ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| CN-1136039-A | [3- (4-phenylpiperazin-1-yl) propylamino, thio and oxy ] -pyridine, pyrimidine and benzene derivatives | HOFFMANN LA ROCHE (CH) | 1996-11-20 | — | — | CN | disclosed |