Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.64 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786798 | 0.86 | DRD2 (0.66) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL1193917 | 0.85 | DRD2 (0.64) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL14066197 | 0.84 | ADRA1A (0.62) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL5307095 | 0.83 | DRD2 (0.69) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL30080716 | 0.81 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL2314632 | 0.81 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL30080714 | 0.81 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL9036478 | 0.81 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL2314625 | 0.81 | KDM4E (0.61) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL4617829 | 0.81 | DRD2 (0.77) | DRD2DRD3ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150527-B1 | ANTHRANILIC ACID DERIVATIVE AS ANTICANCER AGENT AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2011-01-19 | — | — | EP | claimed |
| US-20100168114-A1 | INVERTEBRATE ACETYLCHOLINESTERASE INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2010-07-01 | — | — | US | disclosed |
| US-20080312091-A1 | INVERTEBRATE ACETYLCHOLINESTERASE INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2008-12-18 | — | — | US | disclosed |
| WO-1998015541-A1 | NOVEL ISOXAZOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS | EGIS Gyógyszergyár Rt. (HU) | 1998-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168114-A1 | INVERTEBRATE ACETYLCHOLINESTERASE INHIBITORS | ACHE, BCHE, CHAT | DRD2 2623/4885DRD3 1882/4885ADRA1D 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.