Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23599369 | 0.93 | CCR5 (0.50) | CCR5ALDH1A1RAB9ASLC6A4MAOB | |
| SCHEMBL9125511 | 0.81 | RARB (0.54) | RAB9APTGDRPTGDR2SMN1; SMN2 | |
| SCHEMBL23599817 | 0.80 | CCR5 (0.48) | CCR5ALDH1A1RAB9ASLC6A4MAOB | |
| SCHEMBL5813897 | 0.79 | PTPN1 (0.47) | CCR5ALDH1A1RAB9ASLC6A4MAOB | |
| SCHEMBL4886176 | 0.79 | PTGDR2 (0.73) | ALDH1A1PTGDRPTGDR2 | |
| SCHEMBL17847413 | 0.77 | PTGDR (0.44) | ALDH1A1RAB9APTGDRPTGDR2LMNA | |
| SCHEMBL11479294 | 0.77 | RAB9A (0.47) | CCR5ALDH1A1RAB9ASLC6A4PTPN1 | |
| SCHEMBL5827697 | 0.77 | RARA (0.50) | ALDH1A1PTGDRPTGDR2MAOBLMNA | |
| SCHEMBL6619470 | 0.74 | PTGDR2 (0.42) | ALDH1A1PTGDRPTGDR2HTT | |
| SCHEMBL3312632 | 0.74 | SLC6A4 (0.50) | CCR5ALDH1A1RAB9ASLC6A4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643701-B1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CT INTERNAT DE RECH S BR DERMA (FR) | 2001-12-05 | — | — | EP | disclosed |
| EP-0643701-A1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-03-22 | — | — | EP | disclosed |
| WO-1992021663-A1 | BENZIMIDAZOLE-DERIVED COMPOUNDS, METHOD FOR PREPARING SAME, AND THERAPEUTICAL AND COSMETIC USES THEREOF | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-12-10 | — | — | WO | disclosed |