Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.51 |
| ▸ | HTR7 | P34969 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780152 | 0.83 | HRH3 (0.54) | DRD2HRH3 | |
| Hydrochloric Acid SCHEMBL7470092 | 0.83 | SIGMAR1 (0.51) | DRD2 | |
| SCHEMBL7504553 | 0.80 | KDM1A (0.43) | — | |
| SCHEMBL8517647 | 0.80 | HTT (0.56) | — | |
| SCHEMBL14969305 | 0.79 | ALDH1A1 (0.57) | — | |
| SCHEMBL7780082 | 0.79 | ALDH1A1 (0.54) | — | |
| SCHEMBL14969304 | 0.78 | ALDH1A1 (0.56) | — | |
| SCHEMBL7226538 | 0.78 | ALDH1A1 (0.59) | — | |
| SCHEMBL62691 | 0.78 | HTT (0.64) | HTR1A | |
| SCHEMBL19289840 | 0.78 | HTT (0.64) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140852-A1 | 1,2,3,4-TETRAHYDRONAPHTHALENES AND THEIR PHARAMACEUTICAL USE | AstraZeneca AB (SE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035882-A1 | 1,2,3,4-TETRAHYDRONAPHTHALENES AND THEIR PHARMACEUTICAL USE | ASTRAZENECA AB (SE) | 2000-06-22 | — | — | WO | disclosed |