Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783554 | 0.83 | DAO (0.52) | DAOTAAR1 | |
| SCHEMBL11518915 | 0.82 | MAPT (0.46) | DAOMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL7783960 | 0.80 | DAO (0.55) | DAOTAAR1POLBHTTMAOB | |
| SCHEMBL7783987 | 0.74 | DAO (0.50) | DAOTAAR1GPR84MEN1KMT2A | |
| SCHEMBL16968231 | 0.73 | DAO (0.57) | DAOHRH3TAAR1GPR84MEN1 | |
| SCHEMBL15564166 | 0.73 | DAO (0.57) | DAOHRH3TAAR1GPR84MEN1 | |
| SCHEMBL7785772 | 0.73 | DAO (0.48) | DAOTAAR1HTTALDH1A1LMNA | |
| SCHEMBL7979610 | 0.69 | VHL (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5905968 | 0.68 | IDO1 (0.49) | DAOMEN1KMT2AIDO1HPGD | |
| SCHEMBL5905967 | 0.68 | CYP1A2 (0.48) | POLBIDO1TDO2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144392-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040568-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-07-13 | — | — | WO | disclosed |