Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203195 | 0.76 | LMNA (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1276189 | 0.76 | LMNA (0.42) | AOC3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11649485 | 0.76 | AOC3 (0.42) | AOC3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28081174 | 0.75 | AOC3 (0.47) | AOC3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8079874 | 0.74 | CYP2C19 (0.48) | AOC3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9240062 | 0.74 | CYP2C19 (0.48) | AOC3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28501174 | 0.74 | CES2 (0.49) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3244408 | 0.73 | NPSR1 (0.43) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL643461 | 0.73 | CYP2C19 (0.53) | AOC3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19228532 | 0.73 | CYP2C19 (0.53) | AOC3CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144392-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040568-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-07-13 | — | — | WO | disclosed |