SCHEMBL1276189

SCHEMBL1276189

C=C(c1ccccc1)C(CCC)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
AOC3 Q16853 2/20 0.42
CYP2C19 P33261 3/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP1A2 P05177 1/20 0.40
HSD17B10 Q99714 2/20 0.40
KCNQ2 O43526 1/20 0.39
ATM Q13315 1/20 0.38
HPGD P15428 1/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CHRM2 P08172 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2162293 0.81 AOC3 (0.44) LMNAALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL4824003 0.81 AOC3 (0.44) LMNAALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL11649485 0.78 AOC3 (0.42) LMNAALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL6203195 0.78 LMNA (0.60) LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1
SCHEMBL7786926 0.76 AOC3 (0.41) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL28081174 0.76 AOC3 (0.47) LMNAMAPTAOC3CYP2C19CYP3A4
SCHEMBL9050192 0.76 SLC6A2 (0.38) LMNAALDH1A1MAPTSMN1; SMN2NPSR1
SCHEMBL5034590 0.76 SMN1; SMN2 (0.39) LMNAALDH1A1MAPTSMN1; SMN2NPSR1
SCHEMBL17183806 0.75 EPHX1 (0.46) LMNAALDH1A1KDM4EMAPTSMN1; SMN2
SCHEMBL28501174 0.75 CES2 (0.49) LMNAALDH1A1KDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285746-A1 WATER SOFTENER COMPOSITION Dalli-Werke GmbH & Co. KG (DE) 2011-02-23 EP claimed
WO-2008074402-A1 WATER SOFTENER COMPOSITION DALLI-WERKE GMBH & CO. KG (DE) 2008-06-26 WO claimed