Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.58 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.46 |
| ▸ | ECE1 | P42892 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787127 | 1.00 | CTSS (0.58) | CTSSCTSKPSENENCA2ENPEP | |
| SCHEMBL31069953 | 0.86 | CTSS (0.62) | CTSSCTSKPSENENCA2ENPEP | |
| SCHEMBL9540722 | 0.85 | CTSS (0.61) | CTSSCTSKPSENENCA2 | |
| SCHEMBL9540730 | 0.85 | CTSS (0.61) | CTSSCTSKPSENENCA2 | |
| SCHEMBL31195265 | 0.84 | CTSS (0.52) | CTSSCTSKPSENENCA2ENPEP | |
| SCHEMBL11405307 | 0.83 | CTSS (0.68) | CTSSCTSKPSENENCA2 | |
| SCHEMBL18766187 | 0.83 | CTSS (0.68) | CTSSCTSKPSENENCA2 | |
| SCHEMBL1486143 | 0.82 | APP (0.49) | CTSSCTSKCA2ECE1 | |
| SCHEMBL607848 | 0.82 | APP (0.49) | CTSSCTSKCA2ECE1 | |
| SCHEMBL999894 | 0.82 | APP (0.49) | CTSSCTSKCA2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140979-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040599-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |