SCHEMBL277596

SCHEMBL277596

Oc1nc2ncncc2[nH]1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.51
METAP1 P53582 1/20 0.51
NPY5R Q15761 1/20 0.37
PIK3CG P48736 1/20 0.36
ENPP1 P22413 1/20 0.34
GRIN2B Q13224 10/20 0.33
EGFR P00533 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.31
PDE5A O76074 1/20 0.31
GUSB P08236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31064848 0.75 SMN1; SMN2 (0.52) METAP2METAP1NPY5RENPP1GRIN2B
SCHEMBL7787137 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1
SCHEMBL2011131 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1GRIN2B
SCHEMBL3801779 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1GRIN2B
SCHEMBL5632 0.75 NUDT1 (0.50) METAP2METAP1NPY5REGFR
SCHEMBL375955 0.75 SMN1; SMN2 (0.52) METAP2METAP1NPY5RENPP1GRIN2B
SCHEMBL357003 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1GRIN2B
SCHEMBL3894 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1
SCHEMBL1963575 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1
SCHEMBL30388675 0.75 NUDT1 (0.50) METAP2METAP1NPY5REGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119455413-A Allopurinol desalination and evaporation device and desalination and evaporation method thereof 宜兴市星宇药业有限公司 2025-02-18 CN claimed
CN-119031915-A Methods and compositions for treating skin proliferative disorders and other skin conditions 不对称疗法有限责任公司 2024-11-26 CN claimed
CN-118048204-A Wafer cleaning liquid for cleaning copper surface after chemical mechanical planarization 华中科技大学 2024-05-17 CN claimed
WO-2023202686-A1 COMPOSITION AND METHOD FOR INHIBITING XANTHINE DEHYDROGENASE (XDH) 上海舶望制药有限公司 2023-10-26 WO claimed
CN-115968815-A Induction method for efficiently producing full-male nibea albiflora triploid 浙江省海洋水产研究所 2023-04-18 CN claimed
CN-113416522-A Low-conductivity anti-freezing cooling liquid for new energy power battery and preparation method thereof 上海科鸿能源发展有限公司 2021-09-21 CN claimed
WO-2017062966-A1 ANTIBODIES SPECIFIC FOR 4,6-DIAMINO-5-(FORMYULAMINO) PYRIMIDINE AND USES THEREOF FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2017-04-13 WO claimed
WO-2013181296-A2 COMPOSITIONS AND METHODS FOR MANAGING WEIGHT UNIGEN, INC. (US) 2013-12-05 WO claimed
US-20050026862-A1 Cosmetic or dermatological preparation BEIERSDORF AG 2005-02-03 US claimed
EP-1282680-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2003-02-12 EP claimed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 WO claimed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US claimed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP claimed
US-6011112-A SILYLATED ORGANONITROGEN COMPOUNDS WACKER-CHEMIE GMBH (DE) 2000-01-04 US claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed
EP-0852606-B1 ORGANOPOLYSILOXANE COMPOUNDS CROSS-LINKABLE BY CLEAVING OF ALCOHOLS TO FORM ELASTOMERS WACKER CHEMIE GMBH (DE) 1999-04-14 EP claimed
EP-0634927-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-01-25 EP claimed
US-5321032-A Peptide compounds and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-06-14 US claimed
WO-1993017671-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA STATENS SERUMINSTITUT (DK) 1993-09-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026862-A1 Cosmetic or dermatological preparation OGG1, UNG, MPG METAP2 1389/4885METAP1 1594/4885NPY5R 1895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.