SCHEMBL7787142

SCHEMBL7787142

CC(C)(C)OC(=O)N1CCC(C(C)(C)S(=O)(=O)c2cc(F)cc(C(F)(F)F)c2)CC1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
STS P08842 4/20 0.59
CYP3A4 P08684 2/20 0.52
CACNA1B Q00975 2/20 0.52
NR1I2 O75469 1/20 0.52
TGFBR1 P36897 1/20 0.47
GPR119 Q8TDV5 7/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
DPP4 P27487 1/20 0.42
MMP13 P45452 1/20 0.42
MAPT P10636 1/20 0.42
P2RY14 Q15391 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2191964 0.86 CACNA1B (0.62) STSCYP3A4CACNA1BNR1I2TGFBR1
SCHEMBL17942390 0.84 CYP3A4 (0.54) STSCYP3A4CACNA1BNR1I2TGFBR1
SCHEMBL7787155 0.82 STS (0.53) STSCYP3A4CACNA1BNR1I2TGFBR1
SCHEMBL7787125 0.82 STS (0.58) STSCACNA1BTGFBR1GPR119DPP4
SCHEMBL29530166 0.80 GPR119 (0.52) STSCYP3A4CACNA1BNR1I2TGFBR1
SCHEMBL17948857 0.80 GPR119 (0.52) STSCYP3A4CACNA1BNR1I2TGFBR1
SCHEMBL7860203 0.78 CACNA1B (0.51) STSCYP3A4CACNA1BNR1I2
SCHEMBL17942320 0.77 GPR119 (0.52) STSCYP3A4CACNA1BNR1I2TGFBR1
SCHEMBL29530176 0.77 GPR119 (0.52) STSCYP3A4CACNA1BNR1I2TGFBR1
SCHEMBL13932867 0.77 STS (0.74) STSTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234604-A1 Process for Making Substituted Aryl Sulfone Intermediates LINGHU XIN 2010-09-16 US disclosed
US-20100234604-A1 Process for Making Substituted Aryl Sulfone Intermediates LINGHU XIN 2010-09-16 US disclosed
US-20100234603-A1 Process for Making Substituted Aryl Sulfone Intermediates LINGHU XIN 2010-09-16 US disclosed
US-20100234603-A1 Process for Making Substituted Aryl Sulfone Intermediates LINGHU XIN 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234604-A1 Process for Making Substituted Aryl Sulfone Intermediates SULT1A1, SULT1E1, STS STS 3/4885CYP3A4 70/4885CACNA1B 4731/4885
US-20100234603-A1 Process for Making Substituted Aryl Sulfone Intermediates SULT1A1, SULT1E1, STS STS 3/4885CYP3A4 70/4885CACNA1B 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.